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There is significant evidence that a severe glacial action during the Neoproterozoic era covered much of the planet in a sheet of ice. This hypothesis has been termed the "Snowball Earth", and it is of particular interest as it precedes the Cambrian explosion in which multicellular life forms began to proliferate about 530–540 million years ago.
Since the Cambrian explosion there have been five distinctly identifiable mass extinctions. The last mass extinction occurred some 65 million years ago, when a meteorite collision probably triggered the extinction of the non-avian dinosaurs and other large reptiles, but spared small animals such as mammals, which then resembled shrews. Over the past 65 million years, mammalian life diversified.
Several million years ago, a species of small African ape gained the ability to stand upright. The subsequent advent of human life, and the development of agriculture and further civilization allowed humans to affect the Earth more rapidly than any previous life form, affecting both the nature and quantity of other organisms as well as global climate. By comparison, the oxygen catastrophe, produced by the proliferation of algae during the Siderian period, required about 300 million years to culminate.
The present era is classified as part of a mass extinction event, the Holocene extinction event, the fastest ever to have occurred. Some, such as E. O. Wilson of Harvard University, predict that human destruction of the biosphere could cause the extinction of one-half of all species in the next 100 years. The extent of the current extinction event is still being researched, debated and calculated by biologists.