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Girls develop breasts during puberty, as a result of changing sex hormones, chiefly estrogen, which also has been demonstrated to cause the development of woman-like, enlarged breasts in men, a condition called gynecomastia.
In most cases, the breasts fold down over the chest wall during Tanner stage development. It is typical for a woman's breasts to be unequal in size particularly while the breasts are developing. Statistically it is slightly more common for the left breast to be the larger. In rare cases, the breasts may be significantly different in size, or one breast may fail to develop entirely.
A large number of medical conditions are known to cause abnormal development of the breasts during puberty. Virginal breast hypertrophy is a condition which involves excessive growth of the breasts, and in some cases the continued growth beyond the usual pubescent age. Breast hypoplasia is a condition where one or both breasts fail to develop.